4-Cyano-3-fluorophenylboronic acid (contains varying amounts of Anhydride)
CAS: 843663-18-3
Rif. 3D-FC46550
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Informazioni sul prodotto
- (4-Cyano-3-fluorophenyl)boronic acid
- Boronic acid, (4-cyano-3-fluorophenyl)-
- Boronic acid, B-(4-cyano-3-fluorophenyl)-
- 4-Cyano-3-fluorophenylboronic acid
- 4-Borono-2-fluorobenzonitrile
- 4-Cyano3-fluorophenylboronic acid
4-Cyano-3-fluorophenylboronic acid is a boronic acid that is used in the treatment of primary aldosteronism. This drug inhibits the activity of the enzyme 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1), which converts cortisol to cortisone. It also blocks mineralocorticoid receptors, leading to decreased levels of aldosterone and increased levels of renin. 4-Cyano-3-fluorophenylboronic acid is metabolized by cytochrome P450 enzymes, with the formation of anhydride as one of its metabolites. The pharmacological effects of 4-cyano-3-fluorophenylboronic acid are due to its ability to inhibit 11βHSD1, inhibiting renal reabsorption of sodium and water.
Proprietà chimiche
Richiesta tecnica su: 3D-FC46550 4-Cyano-3-fluorophenylboronic acid (contains varying amounts of Anhydride)
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