n-(2-chloropyrimidin-4-yl)-n,2,3-trimethyl-2h-indazol-6-amine
CAS: 444731-75-3
Rif. 3D-FC59031
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Informazioni sul prodotto
- 2H-Indazol-6-amine, N-(2-chloro-4-pyrimidinyl)-N,2,3-trimethyl-
- N-(2-Chloropyrimidin-4-yl)-N-methyl-2,3-Methyl-2H-indazol-6-amine
- N-(2-Chloropyrimidin-4-yl)-N-methyl-2,3-dimethyl-2H-indazol-6-amine
- N-(2-chloro-4-pyrimidinyl)-N,2,3-trimethyl-2H-Indazol-6-amine
Pazopanib is an anti-cancer drug that belongs to the class of targeted therapies. It is used in the treatment of advanced renal cell carcinoma and soft tissue sarcoma. Pazopanib has been shown to inhibit angiogenesis, which may be due to its ability to inhibit the activation of endothelial cells and their migration. Pazopanib also inhibits tumor growth by interfering with cell cycle progression, which may be due to its ability to inhibit DNA synthesis or protein synthesis. The compound has been found to have a high number of genotoxic impurities, such as dimethyl sulfate and semiquantitative genotoxic impurities such as mutagenic impurities. These impurities can cause adverse effects on DNA, including mutations and chromosomal aberrations.
Proprietà chimiche
Richiesta tecnica su: 3D-FC59031 n-(2-chloropyrimidin-4-yl)-n,2,3-trimethyl-2h-indazol-6-amine
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