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1-[(4-Chlorophenyl)Methyl]-5-(Trifluoromethyl)Benzimidazol-2-Amine
CAS: 150493-34-8
Rif. 3D-FC98097
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Informazioni sul prodotto
- Ns 638
- 1-((4-Chlorophenyl)methyl)-5-(trifluoromethyl)-1H-benzimidazol-2-amine
- 1H-Benzimidazol-2-amine, 1-((4-chlorophenyl)methyl)-5-(trifluoromethyl)-
- 1-(4-chlorobenzyl)-5-(trifluoromethyl)-1H-benzimidazol-2-amine
1-[(4-Chlorophenyl)Methyl]-5-(Trifluoromethyl)Benzimidazol-2-Amine is a molecule that has been shown to cause neuronal death in vitro and in vivo. It binds reversibly to the L-type voltage-gated calcium channels, which are important for neurotransmitter release and neuronal excitability. The blockade of these channels leads to an increase in intracellular calcium concentrations and subsequent neuronal death. 1-[(4-Chlorophenyl)Methyl]-5-(Trifluoromethyl)Benzimidazol-2-Amine has been shown to selectively inhibit granule cell death, while leaving other types of neurons unharmed. This drug can also be used as a blocker of glutamate receptors (NMDA).
Proprietà chimiche
Richiesta tecnica su: 3D-FC98097 1-[(4-Chlorophenyl)Methyl]-5-(Trifluoromethyl)Benzimidazol-2-Amine
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