1-(Pyridin-4-yl)-N-(thiophen-2-ylmethyl)methanamine
CAS: 680185-81-3
Rif. 3D-FCB18581
| 50mg | 245,00 € | ||
| 500mg | 974,00 € |
Informazioni sul prodotto
- 4-Pyridinemethanamine, N-(2-thienylmethyl)-
- N-(2-Thienylmethyl)-4-pyridinemethanamine
- [(Pyridin-4-yl)methyl][(thiophen-2-yl)methyl]amine
- 1-Pyridin-4-yl-N-(thiophen-2-ylmethyl)methanamine
- (Pyridin-4-ylmethyl)(thiophen-2-ylmethyl)amine
THP-1 cells were transfected with pcDNA3.1 plasmid encoding wnt/β-catenin pathway reporter and co-cultured with a mouse neural stem cell line, Cerebellar Granule Cell Line (CGC). The THP-1 cells were stimulated with 1-(pyridin-4-yl)-N-(thiophen-2-ylmethyl)methanamine (PTM), a Wnt ligand that is known to induce follicle development in the ovary, and then treated with the proteasome inhibitor MG132. The data showed that PTM induced ectopic expression of β-catenin in CGCs. This suggests that PTM may be a useful therapeutic tool for the treatment of follicle development disorders in humans due to its ability to induce β-catenin expression.
Proprietà chimiche
Richiesta tecnica su: 3D-FCB18581 1-(Pyridin-4-yl)-N-(thiophen-2-ylmethyl)methanamine
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