4-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoic acid
CAS: 17057-04-4
Rif. 3D-FD116589
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Informazioni sul prodotto
- 4-maleimidobenzoic acid
- 4-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)benzoic acid
- 4-(2,5-Dioxo-2,5-dihydropyrrol-1-yl)benzoic acid
- 4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoate
- 4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoic acid
- 4-Maleimidobenzoic acid
- Benzoic acid, 4-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-
- Benzoic acid, p-maleimido-
- N-(4-Carboxyphenyl)maleimide
- N-(p-Carboxyphenyl)maleimide
- Vedi altri sinonimi
- NSC 14889
- NSC 521355
- p-(N-Maleimido)benzoic acid
- p-Carboxyphenylmaleimide
- p-Maleimidobenzoic acid
4-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoic acid is a monoclonal antibody that binds to the epidermal growth factor receptor (EGFR). It has been shown to be effective in treating glioma patients. 4-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoic acid binds to EGFR with an affinity greater than that of the natural ligand and blocks the binding of EGFR ligands such as epidermal growth factor (EGF), transforming growth factor alpha (TGFα), and platelet derived growth factor (PDGF). This prevents the activation of downstream signaling pathways that lead to cell proliferation, differentiation, and survival. The drug has also been shown to have a high viscosity at low concentrations.
Proprietà chimiche
Richiesta tecnica su: 3D-FD116589 4-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoic acid
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