(4aS,5aR,10aR,11aS,15aR,15bS,16E,18E,19aS,19bR)-2,3,4,4a,5,5a,6,7,8,9,10,10a,11,11a,12,13,14,15,15a,15b,19a,19b-Docosahydro-1H-diind eno[2,1-f:1’,2’-l][1,5]diazacyclotridecine

CAS: 112455-84-2

Rif. 3D-FD158727

Informazioni sul prodotto

• Nome: (4aS,5aR,10aR,11aS,15aR,15bS,16E,18E,19aS,19bR)-2,3,4,4a,5,5a,6,7,8,9,10,10a,11,11a,12,13,14,15,15a,15b,19a,19b-Docosahydro-1H-diind eno[2,1-f:1’,2’-l][1,5]diazacyclotridecine
• Sinonimi: Papuamine(-)-Papuamine, (-)-Papuamine, (4aS,5aR,10aR,11aS,15aR,15bS,16E,18E,19aS,19bR)-2,3,4,4a,5,5a,6,7,8,9,10,10a,11,11a,12,13,14,15,15a,15b,19a,19b-Docosahydro-1H-diindeno[2,1-f:1′,2′-l][1,5]diazacyclotridecine, 112455-84-2, 1H-Diindeno[2,1-f:1′,2′-l][1,5]diazacyclotridecine, 2,3,4,4a,5,5a,6,7,8,9,10,10a,11,11a,12,13,14,15,15a,15b,19a,19b-docosahydro-, (4aS,5aR,10aR,11aS,15aR,15bS,16E,18E,19aS,19bR)-, 1H-Diindeno[2,1-f:1′,2′-l][1,5]diazacyclotridecine, 2,3,4,4a,5,5a,6,7,8,9,10,10a,11,11a,12,13,14,15,15a,15b,19a,19b-docosahydro-, [4aS-(4aR*,5aS*,10aS*,11aR*,15aS*,15bR*,16E,18E,19aR*,19bS*)]-, [4aS-(4aR*,5aS*,10aS*,11aR*,15aS*,15bR*,16E,18E,19aR*,19bS*)]-2,3,4,4a,5,5a,6,7,8,9,10,10a,11,11a,12,13,14,15,15a,15b,19a,19b-Docosahydro-1H-diindeno[2,1-f:1',2'-1][1,5]diazacyclotridecine

Descrizione

(4aS,5aR,10aR,11aS,15aR,15bS,16E,18E,19aS,19bR)-2,3,4,4a,5,5a,6,7,8,9,10,10a,11,,11 a,,12,,13,,14,,15,,15 a,, 15 b-Docosahydro-1H-diindeno[2′1′’2’]1”5]diazacyclotridecine is a cytotoxic and antimycobacterial agent that belongs to the group of indole-derived natural products. It inhibits the mitochondrial respiratory chain and induces apoptosis in cancer cells.

In addition to its potent cytotoxicity against cancer cells in culture and its ability to inhibit autophagy in mcf-7 cells (an immortalized mouse mammary tumor cell line

• Marchio: Biosynth

Proprietà chimiche

• Peso molecolare: 368.6 g/mol
• Formula: C₂₅H₄₀N₂
• Purezza: Min. 95%
• InChI: InChI=1S/C25H40N2/c1-3-10-20-18(8-1)16-24-22(20)12-5-6-13-23-21-11-4-2-9-19(21)17-25(23)27-15-7-14-26-24/h5-6,12-13,18-27H,1-4,7-11,14-17H2/b12-5-,13-6-/t18-,19-,20+,21+,22-,23-,24+,25+/m0/s1
• InChI key: InChIKey=ZKTFUNZCYRUILZ-JJDAYECRSA-N
• SMILES: C1=C/[C@@H]2[C@@H](C[C@@H]3CCCC[C@H]32)NCCCN[C@@H]2C[C@@H]3CCCC[C@H]3[C@@H]2/C=C/1