Dihydrocyclosporin A

CAS: 59865-15-5

Rif. 3D-FD21913

Informazioni sul prodotto

• Nome: Dihydrocyclosporin A
• Sinonimi: 6-[(2S,3R,4R)-3-Hydroxy-4-methyl-2-(methylamino)octanoic acid]cyclosporin A
• Marchio: Biosynth
• Descrizione: Dihydrocyclosporin A is an immunosuppressant, which is a cyclic undecapeptide derived from fungal metabolites, specifically from the soil fungus Tolypocladium inflatum. This compound functions through the inhibition of calcineurin, which is a crucial phosphatase involved in the activation of T-cells. By binding to the intracellular protein cyclophilin, Dihydrocyclosporin A forms a complex that inhibits calcineurin activity, subsequently blocking the transcription of interleukin-2 and other cytokines essential for T-cell proliferation.

Proprietà chimiche

• Peso molecolare: 1,204.63 g/mol
• Formula: C₆₂H₁₁₃N₁₁O₁₂
• Purezza: Min. 95 Area-%
• Colore/Forma: Powder