4-(2,6-Dichlorobenzamido)-N-(piperidin-4-yl)-1H-pyrazole-3-carboxamide HCl
CAS: 902135-91-5
Rif. 3D-FD32785
1g | 956,00 € | ||
2g | 1.307,00 € | ||
25mg | 95,00 € | ||
50mg | 133,00 € | ||
100mg | 188,00 € |
Informazioni sul prodotto
- AT7519 HCl
- At 7519
- N-(4-piperidinyl)-4-(2,6-dichlorobenzoylamino)-1H-pyrazole-3-carboxamide Hcl
- AT-7519(HCl)
4-(2,6-Dichlorobenzamido)-N-(piperidin-4-yl)-1H-pyrazole-3-carboxamide HCl (PD1693) is a small molecule that has been shown to selectively inhibit the transcriptional coactivator HIF-1α. PD1693 inhibits the hypoxic response in tumor cells by preventing the upregulation of HIF-1α. This leads to an increase in hypoxia-inducible genes, which are involved in the regulation of cell proliferation, angiogenesis and apoptosis. PD1693 also affects the expression of genes involved in metabolism and energy production. The subpopulation algorithm was used to identify differentially expressed transcripts in glioma cells following exposure to PD1693. The data from this algorithm were validated using qRT-PCR and Western blotting on human glioma cells.
Proprietà chimiche
Richiesta tecnica su: 3D-FD32785 4-(2,6-Dichlorobenzamido)-N-(piperidin-4-yl)-1H-pyrazole-3-carboxamide HCl
Se si desidera richiedere un preventivo o effettuare un ordine, si prega invece di aggiungere i prodotti desiderati al carrello e poi richiedere un preventivo o un ordine dal carrello. È più veloce, più economico, e potrà beneficiare degli sconti disponibili e di altri vantaggi.