2,4-Dibromo-6-[[[[(4S,5S)-4,5-dihydro-4,5-diphenyl-1-tosyl-1H-imidazol-2-yl]methyl][(S)-1-phenylethyl]amino]methyl]phenol

CAS: 1009582-56-2

Rif. 3D-FD59986

Informazioni sul prodotto

• Nome: 2,4-Dibromo-6-[[[[(4S,5S)-4,5-dihydro-4,5-diphenyl-1-tosyl-1H-imidazol-2-yl]methyl][(S)-1-phenylethyl]amino]methyl]phenol
• Sinonimi: IAP
• CAS: 1009582-56-2

Descrizione

2,4-Dibromo-6-[[[[(4S,5S)-4,5-dihydro-4,5-diphenyl-1-tosyl-1H-imidazol-2-yl]methyl][(S)-1-phenylethyl]amino]methyl]phenol (ZD1839) is a potent apoptosis inducer that inhibits tumor necrosis factor alpha (TNFα) production by binding to the tnf receptor. ZD1839 also induces caspase independent cell death and has been shown to be effective in treating pancreatitis and subcutaneous tumors. This drug has been shown to inhibit the expression of survivin, an important protein for tumor cell survival.

• Marchio: Biosynth

Proprietà chimiche

• Peso molecolare: 773.58 g/mol
• Formula: C₃₈H₃₅Br₂N₃O₃S
• Purezza: Min. 95%
• InChI: InChI=1S/C38H35Br2N3O3S/c1-26-18-20-33(21-19-26)47(45,46)43-35(41-36(29-14-8-4-9-15-29)37(43)30-16-10-5-11-17-30)25-42(27(2)28-12-6-3-7-13-28)24-31-22-32(39)23-34(40)38(31)44/h3-23,27,36-37,44H,24-25H2,1-2H3/t27-,36-,37-/m0/s1
• InChI key: InChIKey=QMNHSXCNPYPSMG-GILITBBJSA-N
• SMILES: Cc1ccc(S(=O)(=O)N2C(CN(Cc3cc(Br)cc(Br)c3O)[C@@H](C)c3ccccc3)=N[C@@H](c3ccccc3)[C@@H]2c2ccccc2)cc1