3-Difluoromethylaniline

CAS: 368-99-0

Rif. 3D-FD77621

Informazioni sul prodotto

• Nome: 3-Difluoromethylaniline

Descrizione

3-Difluoromethylaniline is an organic compound that incorporates a difluoromethyl group. It is a potent, selective and irreversible inhibitor of the protein kinase C (PKC) isoforms, PKC-alpha and PKC-gamma. 3-Difluoromethylaniline binds to the ATP site of the PKC enzyme and prevents ATP from binding, leading to inactivation of the enzyme. The crystal structure of 3-difluoromethylaniline has been determined by X-ray crystallography. The chloride ion forms hydrogen bonds with two hydroxyl groups on the molecule. Disordered regions are observed in electron density maps and mass spectra indicate the presence of 1-4c alkyl chains. Kinase inhibitors like 3-difluoromethylaniline are used as anticancer drugs, to treat psoriasis, arthritis, and other autoimmune diseases. They also have

• Marchio: Biosynth

Proprietà chimiche

• Peso molecolare: 143.13 g/mol
• Formula: C₇H₇F₂N
• Purezza: Min. 95%
• InChI: InChI=1S/C7H7F2N/c8-7(9)5-2-1-3-6(10)4-5/h1-4,7H,10H2
• InChI key: InChIKey=IDFPXKDJNDYDKA-UHFFFAOYSA-N
• SMILES: Nc1cccc(C(F)F)c1