4,4-Difluoro-1-Piperidineethanamine
CAS: 605659-03-8
Rif. 3D-FD82561
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Informazioni sul prodotto
- 1-Piperidineethanamine, 4,4-difluoro-
- 2-(4,4-Difluoropiperidin-1-yl)ethanamine
4,4-Difluoro-1-Piperidineethanamine is a selective CB1 receptor antagonist that has been shown to be a potent and selective antagonist of the cannabinoid receptor. It has been shown to inhibit binding of the agonist [3H]CP55,940 to the CB1 receptor in rat brain membrane preparations with an IC50 value of 0.2 μM and has been used as a tool compound for the discovery of other CB1 receptor antagonists. 4,4-Difluoro-1-Piperidineethanamine is a high potency and selective CB1 receptor antagonist with good oral bioavailability. It has been shown to have high affinity for human CB1 receptors (Ki=0.2 μM), making it useful for studying the role of these receptors in vivo. This drug also inhibits binding of the antagonist [3H]SR141716A to the CB1 receptor with an IC50 value of 1.7 μM
Proprietà chimiche
Richiesta tecnica su: 3D-FD82561 4,4-Difluoro-1-Piperidineethanamine
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