Informazioni sul prodotto
Nome:
5-Formylimidazole-4-carboxylic acid methylester
Sinonimi:
- 1H-imidazole-4-carboxylic acid, 5-formyl-, methyl ester
- Methyl 5-formyl-1H-imidazole-4-carboxylate
Descrizione:
5-Formylimidazole-4-carboxylic acid methylester (5FICM) is a small molecule that has been shown to inhibit the growth of cells by blocking the TNF-α receptor. The molecular modeling data and crystallographic data indicate that 5FICM can bind to the kinase domain of TNF-α receptors, preventing activation of downstream signaling pathways. In knockout mice, 5FICM was found to reduce skin inflammation caused by LPS. It also inhibited tumor necrosis factor (TNF)-α production in epidermal growth factor (EGF)-treated human keratinocytes and inhibited EGF-induced epidermal growth. These data suggest that 5FICM may be a potential therapeutic agent for inflammatory skin diseases, such as psoriasis and atopic dermatitis.
Avviso:
I nostri prodotti sono destinati esclusivamente ad uso di laboratorio. Per qualsiasi altro utilizzo, vi preghiamo di contattarci.
Marchio:
Biosynth
Conservazione lunga:
Note:
Proprietà chimiche
Peso molecolare:
154.12 g/mol
Formula:
C6H6N2O3
Purezza:
Min. 95%
MDL:
Punto di fusione:
Punto di ebollizione:
Punto di infiammabilità:
Densità:
Concentrazione:
EINECS:
Merck:
Codice SA:
