4-Fluoro-a-oxo-benzeneacetaldehyde

CAS: 403-32-7

Rif. 3D-FF23492

Informazioni sul prodotto

• Nome: 4-Fluoro-a-oxo-benzeneacetaldehyde
• Sinonimi: (4-Fluorophenyl)glyoxal(p-Fluorophenyl)glyoxal2-(4-Fluorophenyl)-2-oxoacetaldehyde, (4-Fluorophenyl)(Oxo)Acetaldehyde, (4-Fluorophenyl)(Oxo)Acetaldehyde Hydrate, (4-Fluorophenyl)glyoxal, (p-Fluorophenyl)glyoxal, 2-(4-Fluorophenyl)-2-oxoacetaldehyde, 4-Fluoro-alpha-oxobenzeneacetaldehyde, 4-Fluoro-α-oxobenzeneacetaldehyde, Benzeneacetaldehyde, 4-fluoro-alpha-oxo-, Benzeneacetaldehyde, 4-fluoro-α-oxo-, Brn 2354778, Glyoxal, (p-fluorophenyl)-, NSC 402742, 4-07-00-02133 (Beilstein Handbook Reference)

Descrizione

4-Fluoro-a-oxo-benzeneacetaldehyde belongs to the class of triazolones and is a potent inhibitor of cytochrome P450 (CYP) 2C19. It has been shown that 4-fluoro-a-oxo-benzeneacetaldehyde is more potent than other compounds in this class, such as 6-(2,6-dichlorophenyl)-N-(2,2,2-trifluoroethyl)-4-(4′methylphenyl)-1,3,5 triazinone. The rat brain microsomes were used to assess the inhibitory activity of 4-fluoro-a-oxo benzeneacetaldehyde against CYP 2C19. This compound also inhibits recombinant human CYP 2C19. Treatment with 4FAA inhibited the formation of cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate

• Marchio: Biosynth

Proprietà chimiche

• Peso molecolare: 170.14 g/mol
• Formula: C₈H₅FO₂·H₂O
• Purezza: Min. 95%