3a-Hydroxy pravastatin lactone
CAS: 85798-96-5
Rif. 3D-FH24091
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Informazioni sul prodotto
- 3a-iso-Pravastatin(2S)-2-Methylbutanoic acid (1S,6S,7R,8S,8aR)-1,2,6,7,8,8a-hexahydro-6-hydroxy-7-methyl-8-[2-[(2R,4R)-tetrahydro-4 -hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl esterSQ 31906 lactone
- Butanoic acid, 2-methyl-, 1,2,6,7,8,8a-hexahydro-6-hydroxy-7-methyl-8-(2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl ester
3a-Hydroxy pravastatin lactone is a nitrile that is used as a remedy. It has been shown to decrease the levels of serum cholesterol and triglycerides in hyperlipemic animals. This drug also inhibits microbial growth, with the exception of gram-positive bacteria. 3a-Hydroxy pravastatin lactone is metabolized in the liver by transformation to 3a-hydroxypravastatin, which is then excreted in bile and urine. The transformation process can be inhibited by sulfuric acid or hydrochloric acid. 3a-Hydroxy pravastatin lactone has also been shown to have anti-inflammatory properties (e.g., inhibition of COX activity) and can inhibit arteriosclerosis due to its ability to inhibit lipoprotein lipase and hepatic HMG CoA reductase activity.
Proprietà chimiche
Richiesta tecnica su: 3D-FH24091 3a-Hydroxy pravastatin lactone
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