1H-Indole-5-carboxamidine
CAS: 71889-75-3
Rif. 3D-FI51161
| 250mg | Prezzo su richiesta | ||
| 500mg | Prezzo su richiesta |
Informazioni sul prodotto
- 1H-Indole-5-carboximidamide
1H-Indole-5-carboxamidine is a compound with a hydroxyl group. It has been shown to inhibit the activity of serine protease and coagulation factors, which are important for coagulation. 1H-Indole-5-carboxamidine also inhibits the activity of urokinase-type plasminogen activator, an enzyme that breaks down blood clots. This drug has been shown to inhibit the formation of blood clots in both animal and human studies. The molecular modeling study revealed that 1H-indole-5-carboxamidine binds to benzamidine, a substrate of serine proteases, through hydrogen bonding interactions and chlorine atom. This binding prevents the substrate from interacting with urokinase type plasminogen activator (uPA) and prevents it from cleaving prothrombin to form thrombin, leading to inhibition of coagulation.
Proprietà chimiche
Richiesta tecnica su: 3D-FI51161 1H-Indole-5-carboxamidine
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