Methyl pyrazine-2-carboximidoate
CAS: 74617-55-3
Rif. 3D-FM126603
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Informazioni sul prodotto
- 2-pyrazinecarboximidic acid
- methyl ester
- 2-Pyrazinecarboximidic acid, methyl ester
Methyl pyrazine-2-carboximidoate is an anti-tuberculosis drug that belongs to the class of carboximidamides. It has shown tuberculostatic activity in a number of animal models, including guinea pigs and rats infected with Mycobacterium tuberculosis. Methyl pyrazine-2-carboximidoate binds to the mycobacterial cell membrane, resulting in increased permeability and leakage of intracellular material. The drug also has a beneficial effect on the nervous system, as it inhibits imidazoline receptors.
Methyl pyrazine-2-carboximidoate is synthesized from methyl pyrazine-2-carboxylate and 2-(1H)-aminopyridine hydrochloride (1). The carboxylic acid group is converted to an amide by reaction with ammonia in methanol. This amide can be alkylated using methyl iodide
Proprietà chimiche
Richiesta tecnica su: 3D-FM126603 Methyl pyrazine-2-carboximidoate
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