5-Methylgramine
CAS: 30218-58-7
Rif. 3D-FM52381
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Informazioni sul prodotto
- 3-(Dimethylaminomethyl)-5-methylindole
- Indole, 3-(dimethylamino)methyl-5-methyl-
- Brn 0144975
- Nsc 88884
- 1H-Indole-3-methanamine, N,N,5-trimethyl- (9CI)
- N,N-dimethyl-1-(5-methyl-1H-indol-3-yl)methanamine
5-Methylgramine is a centrally acting adrenergic (5-HT) receptor antagonist that is used for the treatment of allergic disorders and as an antiemetic. It has been shown to be effective in treating allergic rhinitis, urticaria, and pruritus. 5-Methylgramine blocks the binding of 5-hydroxytryptamine at the peripheral 5-ht receptors and also antagonizes the action of endogenous or exogenous histamine at central 5-ht receptors. It has been shown to have a maximal effect on the constrictor responses mediated by the adventitia in guinea pigs. The drug can be given orally or intravenously.
Proprietà chimiche
Richiesta tecnica su: 3D-FM52381 5-Methylgramine
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