3-Methylbenzenesulfonyl chloride

CAS: 1899-93-0

Rif. 3D-FM59089

Informazioni sul prodotto

• Nome: 3-Methylbenzenesulfonyl chloride
• Sinonimi: 3-Toluenesulfonyl chloride, M-toluenesulfonyl chloride, 3-Methylbenzenesulfonyl Chloride, m-Toluenesulphonyl chloride

Descrizione

3-Methylbenzenesulfonyl chloride is a synthetic compound that is a potent 5-HT7 receptor agonist. It has been shown to stimulate locomotor activity and induce convulsions in mice. 3-Methylbenzenesulfonyl chloride was found to have a high safety profile in preclinical studies and did not show any signs of neurotoxicity. The molecule also has functional effects on the 5-HT7 receptor, including partial agonism, antagonism, and inverse agonism. 3-Methylbenzenesulfonyl chloride binds to the pyrazole ring of the 5-HT7 receptor by ring opening or hydrogen bonding with an amide nitrogen atom in its peptidomimetic form. This binding induces conformational changes in the 5-HT7 receptor that lead to G protein activation and downstream signaling pathways that result in antiproliferative effects.

• Marchio: Biosynth

Proprietà chimiche

• Peso molecolare: 190.65 g/mol
• Formula: C₇H₇SO₂Cl
• Purezza: Min. 95%
• Colore/Forma: Clear Liquid
• InChI: InChI=1S/C7H7ClO2S/c1-6-3-2-4-7(5-6)11(8,9)10/h2-5H,1H3
• InChI key: InChIKey=KFPMLWUKHQMEBU-UHFFFAOYSA-N
• SMILES: Cc1cccc(S(=O)(=O)Cl)c1