Netobimin
CAS: 88255-01-0
Rif. 3D-FN26185
5mg | Prezzo su richiesta | ||
10mg | Prezzo su richiesta | ||
25mg | Prezzo su richiesta |
Informazioni sul prodotto
- 2-[[[(Methoxycarbonyl)amino][[2-nitro-5-(propylthio)phenyl]amino]methylene]amino]ethanesulfonic acidHapadexHapasil
- 2-(3-Methoxycarbonyl-2-(2-nitro-5-propylthiophenyl)guanidino)ethansulfonsaeure
- 2-[[[(Methoxycarbonyl)amino][[2-nitro-5-(propylthio)phenyl]amino]methylene]amino]ethanesulfonic acid
- 2-{[(Z)-[(methoxycarbonyl)amino]{[2-nitro-5-(propylsulfanyl)phenyl]amino}methylidene]amino}ethanesulfonic acid
- Ethanesulfonic acid, 2-((((methoxycarbonyl)amino)((2-nitro-5-(propylthio)phenyl)imino)methyl)amino)-
- Ethanesulfonic acid, 2-[[[(methoxycarbonyl)amino][[2-nitro-5-(propylthio)phenyl]amino]methylene]amino]-
- Hapadex
- Hapasil
- Methyl (N'-(2-nitro-5-(propylthio)phenyl)-N-(2-sulfoethyl)amidino)carbamate
- Netobimina
- Vedi altri sinonimi
- Netobimina [Spanish]
- Netobimine
- Netobimine [French]
- Netobiminum
- Netobiminum [Latin]
- Sch 32481
- Unii-U30C54N3Mu
Netobimin is a bicyclic heterocycle that has been shown to have potent anthelmintic activity. It can be used in the treatment of intestinal nematodirus infections and other helminthiasis. Netobimin is administered orally, with an effective dose of 400 mg, and has a complex mechanism of action. It inhibits the glutamate dehydrogenase enzyme in the nematode and prevents it from synthesizing glutamate, which causes paralysis. Netobimin also binds to benzimidazole compounds that are present in the worm’s body, preventing them from binding to GABA receptors on the surface of nerve cells. This binding prevents the formation of a chloride channel between nerve cells, resulting in muscle paralysis. Netobimin also inhibits fatty acid synthesis by blocking acetyl-CoA carboxylase (ACC) and carnitine palmitoyltransferase I (CPT-I).
Proprietà chimiche
Richiesta tecnica su: 3D-FN26185 Netobimin
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