Pradigastat
CAS: 956136-95-1
Rif. 3D-FP103386
| 1mg | Fuori produzione | ||
| 2mg | Fuori produzione | ||
| 5mg | Fuori produzione | ||
| 10mg | Fuori produzione | ||
| 25mg | Fuori produzione |
Informazioni sul prodotto
Nome:
Pradigastat
Sinonimi:
- Lcq 908Nxa
- trans-4-[4-[5-[[6-(Trifluoromethyl)-3-pyridinyl]amino]-2-pyridinyl]phenyl]cyclohexaneacetic acid
Descrizione:
Pradigastat is a small molecule that inhibits the activity of diacylglycerol acyltransferase-2 (DGAT-2) and hepatic lipase. It is used to treat patients with high levels of low-density lipoprotein cholesterol (LDL-C). Pradigastat binds to the active site of DGAT-2 and blocks the transfer of fatty acids from diacylglycerol to triglycerides, which reduces the production of chylomicrons. This compound also inhibits hepatic lipase, which reduces the production and secretion of VLDLs. In addition, pradigastat has antimicrobial effects against bacteria such as Helicobacter pylori, which are known to cause gastric ulcers. Pradigastat also prevents viral replication by inhibiting human macrophages involved in lipid metabolism.
Avviso:
I nostri prodotti sono destinati esclusivamente ad uso di laboratorio. Per qualsiasi altro utilizzo, vi preghiamo di contattarci.
Marchio:
Biosynth
Conservazione lunga:
Note:
Proprietà chimiche
Peso molecolare:
455.47 g/mol
Formula:
C25H24F3N3O2
Purezza:
Min. 95%
InChI:
InChI=1S/C25H24F3N3O2/c26-25(27,28)23-12-10-21(15-30-23)31-20-9-11-22(29-14-20)19-7-5-18(6-8-19)17-3-1-16(2-4-17)13-24(32)33/h5-12,14-17,31H,1-4,13H2,(H,32,33)
InChI key:
InChIKey=GXALXAKNHIROPE-UHFFFAOYSA-N
SMILES:
O=C(O)CC1CCC(c2ccc(-c3ccc(Nc4ccc(C(F)(F)F)nc4)cn3)cc2)CC1
MDL:
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