3-[(Phenylsulfonyl)amino]benzoic acid
CAS: 28547-15-1
Rif. 3D-FP136711
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500mg | Prezzo su richiesta |
Informazioni sul prodotto
- benzoic acid
- 3-[(phenylsulfonyl)amino]-
- 3-(Benzenesulfonamido)benzoic acid
- 3-Benzenesulfonylaminobenzoic acid
- Benzoic acid, 3-[(phenylsulfonyl)amino]-
- Benzoic acid, m-benzenesulfonamido-
- N-(m-Carboxyphenyl)benzenesulfonamide
3-[(Phenylsulfonyl)amino]benzoic acid (PSBA) is a potent inhibitor of the class IIa histone deacetylases (HDACs), which are enzymes that regulate gene expression. It has been shown to inhibit HDAC activity in vitro, leading to increased histone acetylation and increased transcription of target genes. PSBA has also been shown to have other biological activities, such as inhibiting the activity of oxidases and histone methylation. This drug is being researched for its potential use in treating cancer and inflammatory diseases. PSBA has been shown to bind to the active site of HDAC2 with a binding constant of 2 nM, inhibiting the enzyme's ability to remove acetyl groups from lysine residues on histones H3 and H4.
Proprietà chimiche
Richiesta tecnica su: 3D-FP136711 3-[(Phenylsulfonyl)amino]benzoic acid
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