Pranidipine

CAS: 99522-79-9

Rif. 3D-FP33696

Informazioni sul prodotto

• Nome: Pranidipine
• Sinonimi: (E)-Cinnamyl methyl (+-)-1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate, 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-methyl 5-[(2E)-3-phenyl-2-propen-1-yl] ester, 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, methyl (2E)-3-phenyl-2-propenyl ester, 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, methyl 3-phenyl-2-propenyl ester, (E)-, Acalas, Brn 5654325, Ccris 6666, Frc 8411, Methyl cinnamyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate, Opc 13340, Pranidipine [INN], Unii-9Des9Qvh58, methyl (2E)-3-phenylprop-2-en-1-yl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate, trans-Cinnamyl methyl 4-(3-nitrophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

Descrizione

Pranidipine is a calcium channel blocker and a positive inotrope. It is used for the treatment of high blood pressure, as well as chronic heart failure. Pranidipine also inhibits the action of cyclase, which is an enzyme that catalyzes the formation of cAMP from ATP. This drug may be used to treat pain due to bowel disease by blocking voltage-dependent calcium channels on neurons in the intestine. The reaction mechanism of pranidipine is inhibition of cyclase, but it also inhibits other enzymes such as phosphodiesterases and lipoxygenases. Significant interactions with other drugs have been observed using rat studies. Pranidipine has been shown to decrease glomerular filtration rate and renal clearance, leading to toxicity in rats at high doses. This drug also causes cardiac arrhythmia, drug interactions, and liver damage at higher doses.

• Marchio: Biosynth

Proprietà chimiche

• Peso molecolare: 448.47 g/mol
• Formula: C₂₅H₂₄N₂O₆
• Purezza: Min. 95%