Quinapril diketopiperazine

CAS: 103733-49-9

Rif. 3D-FQ27370

Informazioni sul prodotto

• Nome: Quinapril diketopiperazine
• Sinonimi: (a-S,3S,11aS)-1,3,4,6,11,11a-Hexahydro-3-methyl-1,4-dioxo-a-(2-phenylethyl)-2H-pyrazino[1,2-b]isoquinoline-2-acetic acidPD 109488, (aS,3S,11aS)-1,3,4,6,11,11a-Hexahydro-3-methyl-1,4-dioxo-a-(2-phenylethyl)-2H-pyrazino[1,2-b]isoquinoline-2-acetic Acid, Pd 109488, Quinapril Diketopiperazine, ethyl (2S)-2-[(3S,11aS)-3-methyl-1,4-dioxo-3,6,11,11a-tetrahydropyrazino[4,5-b]isoquinolin-2-yl]-4-phenyl-butanoate

Descrizione

Quinapril diketopiperazine is an analytical reagent that is used in the determination of the rate of reaction of a chemical substance with quinapril. Quinapril is a dihydropyridine derivative that acts as a vasodilator and antihypertensive drug. The quinapril molecule has a hydroxyl group on its 2-position, which is converted to an amine by the acidic hydrolysis. This amine then reacts with the carboxylic acid to form the diketopiperazine. The reaction rate can be determined by measuring the absorbance at 410 nm using a spectrophotometer and comparing it to a calibration curve.
The chromatographic separation method for determining the concentration of quinapril in solution involves passing an organic solution through a column filled with silica gel or alumina and eluting it with solvents containing different polarities, such as water, methanol, acetone

• Marchio: Biosynth

Proprietà chimiche

• Peso molecolare: 420.5 g/mol
• Formula: C₂₅H₂₈N₂O₄
• Purezza: Min. 95%
• InChI: InChI=1S/C25H28N2O4/c1-3-31-25(30)21(14-13-18-9-5-4-6-10-18)27-17(2)23(28)26-16-20-12-8-7-11-19(20)15-22(26)24(27)29/h4-12,17,21-22H,3,13-16H2,1-2H3/t17-,21-,22-/m0/s1
• InChI key: InChIKey=NDDYKENLGBOEPD-HSQYWUDLSA-N
• SMILES: CCOC(=O)[C@H](CCc1ccccc1)N1C(=O)[C@@H]2Cc3ccccc3CN2C(=O)[C@@H]1C