(S)-Rabeprazole

CAS: 177795-59-4

Rif. 3D-FR27402

Informazioni sul prodotto

• Nome: (S)-Rabeprazole
• Sinonimi: 2-[(S)-[[4-(3-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazoleS-(-)-Rabeprazole
• CAS: 177795-59-4

Descrizione

Rabeprazole is a proton pump inhibitor that inhibits the production of stomach acid by blocking the H+/K+ ATPase enzyme in the gastric parietal cells. It is used for treatment of acid reflux disease and other conditions related to excess stomach acid production, such as Zollinger-Ellison syndrome. Rabeprazole has been shown to inhibit cytochrome P450 2C19 (CYP2C19) in human liver microsomes and recombinant CYP2C19 in vitro. This inhibition was stereoselective and correlated with plasma concentrations. These findings suggest that rabeprazole may have a role in drug-drug interactions involving CYP2C19 substrates.

• Marchio: Biosynth

Proprietà chimiche

• Peso molecolare: 359.44 g/mol
• Formula: C₁₈H₂₁N₃O₃S
• Purezza: Min. 95%
• InChI: InChI=1S/C18H21N3O3S/c1-13-16(19-9-8-17(13)24-11-5-10-23-2)12-25(22)18-20-14-6-3-4-7-15(14)21-18/h3-4,6-9H,5,10-12H2,1-2H3,(H,20,21)/t25-/m0/s1
• InChI key: InChIKey=YREYEVIYCVEVJK-VWLOTQADSA-N
• SMILES: COCCCOc1ccnc(C[S@](=O)c2nc3ccccc3[nH]2)c1C