Ralfinamide
CAS: 133865-88-0
Rif. 3D-FR98311
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Informazioni sul prodotto
- (2S)-2-[[[4-[(2-Fluorophenyl)methoxy]phenyl]methyl]amino]propanamide
- (S)-2-[[4-[(2-Fluorobenzyl)oxy]benzyl]amino]propanamide
- N~2~-{4-[(2-fluorobenzyl)oxy]benzyl}-L-alaninamide
- Priralfinamide
- Propanamide, 2-[[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]amino]-, (2S)-
- Propanamide, 2-[[[4-[(2-fluorophenyl)methoxy]phenyl]methyl]amino]-, (S)-
Ralfinamide is a potent and selective blocker of the neuronal sodium channel. It has been shown to inhibit viral replication in cells infected with HIV-1, HSV-2, and vesicular stomatitis virus. Ralfinamide also produces a dose-dependent inhibition of rotarod performance in mice and inhibits acid formation in rat stomachs. This drug has been shown to have pressor effects at high doses and causes whole-cell recordings from neurons to be more sensitive to depolarization by an increase in intracellular chloride ions. Ralfinamide mesylate is a crystalline polymorph that is more soluble than ralfinamide hydrochloride, making it more suitable for oral administration.
Proprietà chimiche
Richiesta tecnica su: 3D-FR98311 Ralfinamide
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