Thiostrepton

CAS: 1393-48-2

Rif. 3D-FT28240

Informazioni sul prodotto

• Nome: Thiostrepton
• Sinonimi: Alaninamide, <span class="text-smallcaps">L</smallcap>-threonyl-(4S)-2-[(1Z)-1-amino-1-propenyl]-4,5-dihydro-4-thiazolecarbonyl-2-[(1S,2S,3R)-1-amino-2,3-dihydroxy-2-methylbutyl]-4-thiazolecarbonyl-2-[(5R,6S)-6-[2-[(1S,2R)-1-amino-2-hydroxypropyl]-4-thiazolyl]-5-[[N-[(7R,8S)-2-carboxy-7,8-dihydro-8-hydroxy-4-[(1S)-1-hydroxyethyl]-7-quinolinyl]-<smallcap>L</smallcap>-isoleucyl-<smallcap>L</smallcap>-alanyl-2,3-didehydroalanyl-<smallcap>L</span>-alanyl]amino]-5-(4-carboxy-2-thiazolyl)-3,4,5,6-tetrahydro-2-pyridinyl]-4-thiazolecarbonyl-2,3-didehydroalanyl-2,3-didehydro-, (1′→4)-lactone, (4→1)-lactam, Alaninamide, N-[(7R,8S)-2-carboxy-7,8-dihydro-8-hydroxy-4-[(1S)-1-hydroxyethyl]-7-quinolinyl]-<span class="text-smallcaps">L</smallcap>-isoleucyl-<smallcap>L</smallcap>-alanyl-2,3-didehydroalanyl-<smallcap>L</span>-alanyl-2-[(4aR,11S,14Z,18S,21S,28S,32aS)-4a-amino-21-[(1S,2R)-1,2-dihydroxy-1-methylpropyl]-14-ethylidene-3,4,4a,9,10,11,12,13,14,18,19,20,21,27,28,32a-hexadecahydro-11,28-bis[(1R)-1-hydroxyethyl]-9,12,19,26-tetraoxo-17H,26H-8,5:18,15:25,22:32,29-tetranitrilo-5H,15H-pyrido[3,2-m][1,11,17,24,4,7,20,27]tetrathiatetraazacyclotriacontin-2-yl]-4-thiazolecarbonyl-2,3-didehydroalanyl-2,3-didehydro-, (1→5²⁸)-lactone, Bryamycin, Gargon, N-{3-[(3-amino-3-oxoprop-1-en-2-yl)amino]-3-oxoprop-1-en-2-yl}-2-[(11E)-37-(butan-2-yl)-18-(2,3-dihydroxybutan-2-yl)-11-ethylidene-59-hydroxy-8,31-bis(1-hydroxyethyl)-26,40,46-trimethyl-43-methylidene-6,9,16,23,28,38,41,44,47-nonaoxo-27-oxa-3,13,20,56-tetrathia-7,10,17,24,36,39,42,45,48,52,58,61,62,63,64-pentadecaazanonacyclo[23.23.9.3~29,35~.1~2,5~.1~12,15~.1~19,22~.1~54,57~.0~1,53~.0~32,60~]tetrahexaconta-2(64),4,12(63),19(62),21,29,31,33,51,54,57,60-dodecaen-51-yl]-1,3-thiazole-4-carboxamide (non-preferred name), NSC 170365, NSC 81722, Thiactin, Thiostrepton A
• CAS: 1393-48-2

Descrizione

Thiostrepton is a chemical compound that acts as an antibiotic. It binds to the enzyme DNA-dependent RNA polymerase, preventing transcription and replication. Thiostrepton has been shown to have minimal toxicity in laboratory animals and humans and has been extensively tested for pharmacological properties. It is also stable in biological fluids, making it an ideal candidate for use as a diagnostic tool. The drug has been shown to inhibit the activity of other enzymes such as alkanoic acid, which may have synergistic effects with thiostrepton.

• Marchio: Biosynth

Proprietà chimiche

• Peso molecolare: 1,664.89 g/mol
• Formula: C₇₂H₈₅N₁₉O₁₈S₅
• Purezza: Min. 95%
• Colore/Forma: White To Light (Or Pale) Yellow Solid