a-Terthienylmethanol
CAS: 13059-93-3
Rif. 3D-FT42641
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Informazioni sul prodotto
- 5-Hydroxymethyl-2,2',2''-terthiophene
- 5-Hydroxymethyl-2,2′,2′′-terthiophene
- 5-Hydroxymethyl-a-terthienyl
- 5-hydroxymethyl-2,2':5',2''-Terthiophene
- 5-hydroxymethyl-2,2′:5′,2′′-Terthiophene
- [2,2'-Bithiophene]-5-methanol,5'-(2-thienyl)-
- [2,2′:5′,2′′-Terthiophene]-5-methanol
a-Terthienylmethanol is a reactive oxygen species (ROS) that is generated in the human endometrium. ROS, such as a-terthienylmethanol, are produced by NADPH oxidase and can cause apoptosis in cancer cells. This molecule has shown to have anticancer activity against endometrial cancer cells. It also induces morphological changes such as cell shrinkage and nuclear condensation, which may be due to ROS production. a-Terthienylmethanol has shown to inhibit growth of endometrial cancer cells by inhibiting protein synthesis and DNA replication. The mechanism of this inhibition is not yet known but may be related to an interaction with the cell membrane or interference with transcription factors.
Proprietà chimiche
Richiesta tecnica su: 3D-FT42641 a-Terthienylmethanol
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