Voriconazole N-oxide
CAS: 618109-05-0
Rif. 3D-FV28722
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Informazioni sul prodotto
- (a-R,b-S)-a-(2,4-Difluorophenyl)-5-fluoro-b-methyl-a-(1H-1,2,4-triazol-1-ylmethyl)-1-oxide-4-pyrimidineethanolUK 121265
Voriconazole N-oxide is a metabolite of voriconazole, an inhibitor of the cytochrome P450 enzyme. It is used in human liver and other tissues to inhibit the activity of p450 enzymes. Voriconazole N-oxide has been shown to be active against a wide range of bacterial, fungal, and parasitic infections. The n-oxide form of voriconazole has been shown to have higher potency than the parent drug in some cases, but less so in others. In one study, voriconazole N-oxide was found to be more effective at inhibiting oxidative DNA damage than voriconazole. This is due to its ability to react with dioxygen in a noncompetitive manner.
Proprietà chimiche
Richiesta tecnica su: 3D-FV28722 Voriconazole N-oxide
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