Informazioni sul prodotto
- 1,10-Phenanthroline, 4-methyl-
4-Methyl-1,10-phenanthroline (4MP) is a functional molecule that has been extensively studied for its use as an anticancer agent. 4MP is a racemic mixture of 4-methyl and 1,10-phenanthroline enantiomers. It has shown anticancer activity in the L1210 murine leukemia model and cisplatin-resistant human ovarian cancer cells. The binding constants of 4MP to DNA depend on the orientation of the molecule with respect to the DNA helix. The cis configuration binds more tightly than the trans configuration, which may be due to steric hindrance. 4MP inhibits luminescence by interacting with micelles and forming aggregates in water.
Proprietà chimiche
Richiesta tecnica su: 3D-GBA30128 4-Methyl-1,10-phenanthroline
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