10Z-Hymenialdisine
CAS: 82005-12-7
Rif. 3D-HDA00512
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Informazioni sul prodotto
- (4E)-4-(2-amino-5-oxo-1,5-dihydro-4H-imidazol-4-ylidene)-2-bromo-4,5,6,7-tetrahydropyrrolo[2,3-c]azepin-8(1H)-one
- (4Z)-4-(2-Amino-1,5-dihydro-5-oxo-4H-imidazol-4-ylidene)-2-bromo-4,5,6,7-tetrahydropyrrolo[2,3-c]azepin-8(1H)-one
- (Z)-Hymenialdisine
- Hymenialdesine
- Hymenialdisine
- Pyrrolo[2,3-c]azepin-8(1H)-one, 4-(2-amino-1,5-dihydro-5-oxo-4H-imidazol-4-ylidene)-2-bromo-4,5,6,7-tetrahydro-, (4Z)-
- Pyrrolo[2,3-c]azepin-8(1H)-one, 4-(2-amino-1,5-dihydro-5-oxo-4H-imidazol-4-ylidene)-2-bromo-4,5,6,7-tetrahydro-, (Z)-
- pyrrolo[2,3-c]azepin-8(1H)-one, 4-(2-amino-1,5-dihydro-5-oxo-4H-imidazol-4-ylidene)-2-bromo-4,5,6,7-tetrahydro-, (4E)-
Hymenialdisine is a novel inhibitor of kinases that has been shown to be effective against cancer cells and hepatocyte-like cells. It has been found to inhibit the activity of a number of kinases, including Epidermal Growth Factor Receptor (EGFR), c-Src, and p38 mitogen-activated protein kinase (MAPK). The molecular docking analysis revealed that hymenialdisine can bind within the ATP binding pocket of these kinases. Hymenialdisine also showed biological properties in a sponge model system as well as in marine organisms such as sponges and sea anemones.
Proprietà chimiche
Richiesta tecnica su: 3D-HDA00512 10Z-Hymenialdisine
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