1-Phenyl-2,3,4,9-tetrahydro-1H-beta-carboline-3-carboxylic acid
CAS: 82789-18-2
Rif. 3D-HDA78918
| 50mg | 264,00 € | ||
| 500mg | 1.054,00 € |
Informazioni sul prodotto
- 1H-Pyrido[3,4-b]indole-3-carboxylic acid, 2,3,4,9-tetrahydro-1-phenyl-
- 1-Phenyl-2,3,4,9-tetrahydro-1H-b-carboline-3-carboxylic acid
- 1-Phenyl-2,3,4,9-tetrahydro-1H-beta-carboline-3-carboxylic acid
1-Phenyl-2,3,4,9-tetrahydro-1H-beta-carboline-3-carboxylic acid (1PC) is a potent inhibitor of HIV RNA polymerase that has been shown to be active against HIV in cell culture. 1PC is a ligand for the HIV transcriptase and binds to the enzyme's active site. 1PC prevents the formation of the RNA primer needed for transcription by binding to the primer binding site on the enzyme. The compound also inhibits nonnucleoside reverse transcriptase inhibitors, such as zidovudine and lamivudine. This inhibition is through competitive inhibition at the active site of the enzyme and not through covalent bonding to an amino acid residue on the protein. 1PC also has antiviral activity against influenza virus A/WSN/33 (H1N1), human coronavirus 229E, human coronavirus OC43 (H2N2
Proprietà chimiche
Richiesta tecnica su: 3D-HDA78918 1-Phenyl-2,3,4,9-tetrahydro-1H-beta-carboline-3-carboxylic acid
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