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4-Fluoro-N-methyl-N-[4-[6-[(1-methylethyl)amino]-4-pyrimidinyl]-2-thiazolyl]benzamide
CAS: 932737-65-0
Rif. 3D-HMB73765
| 1mg | Fuori produzione | ||
| 5mg | Fuori produzione | ||
| 10mg | Fuori produzione | ||
| 25mg | Fuori produzione | ||
| 50mg | Fuori produzione |
Informazioni sul prodotto
Nome:
4-Fluoro-N-methyl-N-[4-[6-[(1-methylethyl)amino]-4-pyrimidinyl]-2-thiazolyl]benzamide
Descrizione:
4-Fluoro-N-methyl-N-[4-[6-[(1-methylethyl)amino]-4-pyrimidinyl]-2-thiazolyl]benzamide is an allosteric modulator of metabotropic glutamate receptors. It has been shown to inhibit lipid biosynthesis in cells (e.g., COS cells) and has been used as a radiation sensitizer for low energy photon therapy for cancer treatment. 4FMTAB binds to the extracellular signal domain of the metabotropic glutamate receptor, which is a G protein coupled receptor. This binding inhibits the signal detection process, leading to a decrease in intracellular cAMP levels and subsequent inhibition of protein synthesis. 4FMTAB also inhibits translation by binding to the ribosome and inhibiting peptide bond formation between amino acids.
Avviso:
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Marchio:
Biosynth
Conservazione lunga:
Note:
Proprietà chimiche
Peso molecolare:
371.43 g/mol
Formula:
C18H18FN5OS
Purezza:
Min. 95%
MDL:
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