Pepstatin A (Synthetic)

CAS: 26305-03-3

Rif. 3D-IPA-3998-PI

Informazioni sul prodotto

• Nome: Pepstatin A (Synthetic)
• Marchio: Biosynth
• Descrizione: Pepstatin A is a natural product that has been synthesized for use as an inhibitor of proteolytic enzymes. It inhibits the activity of a wide range of proteases and is used in vitro to study the biochemical properties of these enzymes. Pepstatin A inhibits the activity of many important proteases, including those involved in infectious diseases, such as HIV and hepatitis C virus. Pepstatin A binds to the active site on serine proteases, blocking access by their substrates and thereby inhibiting enzyme activity. The binding site is highly conserved among different types of serine protease, with approximately 90% homology between trypsin and chymotrypsin. The inhibitory mechanism involves a specific interaction between pepstatin A's hydrophobic side chain and the catalytic triad residues His57, Asp102, and Ser195 in trypsin or His57, Asp102, and Ser188 in chymotrypsin.

Proprietà chimiche

• Peso molecolare: 685.89 g/mol
• Formula: C₃₄H₆₃N₅O₉
• Purezza: Min. 95%