Ivacaftor hydrate
CAS: 1134822-07-3
Rif. 3D-JVB82207
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Informazioni sul prodotto
Ivacaftor is a small molecule that inhibits the CFTR protein. It is used as a research tool to study the function of CFTR and as an experimental treatment for cystic fibrosis. Ivacaftor is a potent, selective inhibitor of the CFTR protein with activity against all known mutations in the CFTR gene, including those that confer resistance to other drugs. Ivacaftor is not an agonist or antagonist, but instead blocks the channel by binding at its open state. The efficacy of ivacaftor was demonstrated in animal models and in clinical trials involving patients with cystic fibrosis who have specific mutations in their CFTR gene.
Ivacaftor has been shown to be effective in treating symptoms of cystic fibrosis such as pulmonary exacerbations, weight loss, and sweat chloride levels.
Proprietà chimiche
Richiesta tecnica su: 3D-JVB82207 Ivacaftor hydrate
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