Acetaminophen D-glucuronide

CAS: 16110-10-4

Rif. 3D-MA09392

Informazioni sul prodotto

• Nome: Acetaminophen D-glucuronide
• Sinonimi: Paracetamol-O-D-glucuronidep-Acetylaminophenol-O-D-glucuronide, 4-(Acetylamino)phenyl β-<span class="text-smallcaps">D</span>-glucopyranosiduronic acid, 4-(acetylamino)phenyl beta-D-glucopyranosiduronic acid, 4-Glucuronosidoacetanilide, 4-Hydroxyacetanilide glucuronide, Acetanilide glucuronide, Deethylphenacetin glucuronide, Glucopyranosiduronic acid, p-acetamidophenyl, β-<span class="text-smallcaps">D</span>-, N-Acetyl-4-aminophenol glucuronide, N-Acetyl-4-glucuronosidoaniline, N-Acetyl-p-aminophenyl glucuronide, Paracetamol O-glucuronide, Paracetamol glucuronide, Paracetamol β-glucuronide, Pcm-G, beta-D-Glucopyranosiduronic acid, 4-(acetylamino)phenyl, p-Acetamidophenyl <span class="text-smallcaps">D</span>-glucosiduronic acid, p-Acetamidophenyl glucosiduronic acid, p-Acetamidophenyl glucuronide, β-<span class="text-smallcaps">D</span>-Glucopyranosiduronic acid, 4-(acetylamino)phenyl, β-<span class="text-smallcaps">D</span>-Glucopyranosiduronic acid, p-acetamidophenyl, β-<span class="text-smallcaps">D</span>-Glucosiduronic acid, p-acetamidophenyl
• CAS: 16110-10-4

Descrizione

Acetaminophen D-glucuronide (APG) is a metabolite of acetaminophen. It is a major metabolite produced by the liver after acetaminophen is converted to APG by UDP-glucuronyltransferase. The biological properties of APG are similar to acetaminophen, but it has been shown that APG may have greater potency than acetaminophen in some tissues. For example, in vitro studies using hepatocyte-like cells have shown that APG has higher activity than acetaminophen on the induction of CYP2E1 and CYP3A4, two enzymes involved in drug metabolism. Acetaminophen D-glucuronide can be detected in blood samples for up to 48 hours after administration of an intravenous dose of acetaminophen, which provides a more precise measurement than other methods such as plasma concentrations or urinary excretion measurements.

• Marchio: Biosynth

Proprietà chimiche

• Peso molecolare: 327.29 g/mol
• Formula: C₁₄H₁₇NO₈
• Purezza: Min. 95%
• Colore/Forma: White Powder