2-Acetamido-1,4-imino-1,2,4-trideoxy-L-arabinitol
CAS: 944329-24-2
Rif. 3D-MA16570
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Informazioni sul prodotto
- N-[(3S,4R,5S)-4-Hydroxy-5-(hydroxymethyl)-3-pyrrolidinyl]acetamideLABNAc
2-Acetamido-1,4-imino-1,2,4-trideoxy-L-arabinitol is a competitive inhibitor of the enzyme arabinitol dehydrogenase. This compound has been shown to be an enantiomer of 1,4-imino-1,2,4-trideoxyglucitol and inhibits the growth of Mycobacterium tuberculosis in vitro assays. 2AITDG also has inhibitory properties against macrophage cells and noncompetitive inhibitors against glycoprotein glycoconjugates. 2AITDG binds to endoplasmic reticulum chaperones such as BiP/Grp78 to inhibit protein folding and cellular proliferation. It may also inhibit protein synthesis by binding to ribosomes or blocking the activity of factors involved in transcription and translation.
Proprietà chimiche
Richiesta tecnica su: 3D-MA16570 2-Acetamido-1,4-imino-1,2,4-trideoxy-L-arabinitol
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