2-Amino-2,3,5-trideoxy-3-methyl-L-arabinonic acid-γ-lactone hydrochloride
CAS: 42417-44-7
Rif. 3D-MA31272
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Informazioni sul prodotto
- 2(3H)-Furanone,3-aminodihydro-4,5-dimethyl-, hydrochloride, [3R-(3a,4b,5a)]-
2-Amino-2,3,5-trideoxy-3-methyl-L-arabinonic acid-gamma-lactone hydrochloride is a lipid biosynthesis inhibitor that blocks the first step of this pathway by inhibiting the enzyme d-arabinose 4,5-diphosphate aldolase. This compound inhibits bacterial growth and leads to cell lysis. It has been shown to be active against cryptococcus neoformans and Candida neopformans. 2AADL has also been shown to inhibit the production of cell wall polysaccharides in C. neoformans and other fungi. 2AADL is thought to bind to the cell membrane through its alcohol group, which may lead to changes in the redox potential of the cells.
Proprietà chimiche
Richiesta tecnica su: 3D-MA31272 2-Amino-2,3,5-trideoxy-3-methyl-L-arabinonic acid-γ-lactone hydrochloride
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