(2S,5S)-Bishydroxymethyl-(3R,4R)-bishydroxypyrrolidine
CAS: 105015-44-9
Rif. 3D-MB18811
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Informazioni sul prodotto
- (2S,3R,4R,5S)-2,5-bis(hydroxymethyl)pyrrolidine-3,4-diol
(2S,5S)-Bishydroxymethyl-(3R,4R)-bishydroxypyrrolidine is a cytotoxic agent that can be used as a reagent to hydrogenolyze chloride. It is also a nucleophilic anion that can react with cisplatin to form the corresponding platinum complex. This anion has been shown to be cytotoxic against Mcf-7 cells in vitro and can inhibit DNA synthesis. (2S,5S)-Bishydroxymethyl-(3R,4R)-bishydroxypyrrolidine may also inhibit protein synthesis by reacting with anthraquinone or benzylidenation products of azasugar. The synthesis of the latter product is catalyzed by the enzyme benzylidene-pyridine dioxygenase which activates carbonyls and azasugars to form benzylic hydrazones. These reactions are sequential and have been shown to occur in
Proprietà chimiche
Richiesta tecnica su: 3D-MB18811 (2S,5S)-Bishydroxymethyl-(3R,4R)-bishydroxypyrrolidine
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