1,4-Dideoxy-1,4-imino-D-xylitol HCl
CAS: 186759-56-8
Rif. 3D-MD10116
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Informazioni sul prodotto
- (2R,3R,4S)-2-(hydroxymethyl)pyrrolidine-3,4-diol
- 3,4-Pyrrolidinediol, 2-(hydroxymethyl)-, (2α,3β,4β)-
- <span class="text-smallcaps">DL</span>-Ribitol, 1,4-dideoxy-1,4-imino-
- rel-(2R,3R,4S)-2-(Hydroxymethyl)-3,4-pyrrolidinediol
1,4-Dideoxy-1,4-imino-D-xylitol HCl (DDX) is a potent inhibitor of the enzyme carboxypeptidase A2. DDX has been shown to inhibit the growth of HIV in vitro and in vivo. DDX also inhibits the production of proinflammatory cytokines and neurotrophic factors from HL60 cells. It has been shown to be a potential drug target for the treatment of infectious diseases such as alphaviruses, which produce a severe neuroinvasive disease in humans. DDX binds to dna with high affinity and specificity, but does not bind to RNA or proteins. DDX inhibits mitochondrial membrane potential by binding to ATP synthase and blocking the synthesis of ATP. DDX has also been shown to have an anti-oxidative injury effect on mitochondria, which may contribute to its inhibition of viral replication.
Proprietà chimiche
Richiesta tecnica su: 3D-MD10116 1,4-Dideoxy-1,4-imino-D-xylitol HCl
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