N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine
CAS: 912569-84-7
Rif. 3D-MLB56984
5mg | Prezzo su richiesta | ||
10mg | Prezzo su richiesta | ||
25mg | Prezzo su richiesta | ||
50mg | Prezzo su richiesta |
Informazioni sul prodotto
N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine is a cytotoxic drug that belongs to the class of maytansinoids. It is metabolized in vivo to produce cytotoxic metabolites which inhibit protein synthesis by binding to ribosomes, preventing peptide bond formation. The preclinical studies have shown that N2'-deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine has a better therapeutic index than other maytansinoids, with fewer side effects. In animal models, N2'-deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine showed efficacy against human tumor cells and was not toxic to normal cells. This agent also showed no impurities when incubated with human liver microsomes and it was well tolerated in clinical trials in humans
Proprietà chimiche
Richiesta tecnica su: 3D-MLB56984 N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine
Se si desidera richiedere un preventivo o effettuare un ordine, si prega invece di aggiungere i prodotti desiderati al carrello e poi richiedere un preventivo o un ordine dal carrello. È più veloce, più economico, e potrà beneficiare degli sconti disponibili e di altri vantaggi.