Informazioni sul prodotto
- t-Butyloxycarbonyl-L-Glutaminyl-L-Alanyl-L-Arginine 4-Methyl-Coumaryl-7-Amide Boc-Gln-Ala-Arg-MCA Boc-QAR-AMC
Boc-Gln-Ala-Arg-AMC is a peptide inhibitor of the human voltage-gated potassium channel Kv1.2. It is a competitive antagonist of the Kv1.2 channel and has been shown to inhibit the proliferation of human cancer cells in vitro and in vivo. Boc-Gln-Ala-Arg-AMC binds to the S4 segment of Kv1.2, which is located on the surface of the channel. This binding prevents opening of the voltage sensor domain and thereby reduces or eliminates current flow through the channel. Boc-Gln-Ala-Arg-AMC can be used as a research tool for studying protein interactions with ion channels, as well as for understanding receptor activation mechanisms and ligand binding sites.
Proprietà chimiche
Richiesta tecnica su: 3D-MQR-3135-V Boc-Gln-Ala-Arg-AMC (5 mg vial)
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