1-(4-Aza-8-hydroxy-6-oxo)oct-2-en-1-oylimidazole
CAS: 89186-34-5
Rif. 3D-PDA18634
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Informazioni sul prodotto
- 4-Hydroxy-1-[[3-(1H-imidazol-1-yl)-3-oxo-1-propen-1-yl]amino]-2-butanone
The 1-aza-8-hydroxy-6-oxo-oct-2-en-1-oylimidazole is a prodrug that is hydrolyzed to form the active compound clavulanate. It can be used for the treatment of infections caused by beta lactamase producing bacteria such as penicillinase producing staphylococci and beta lactamase producing streptococci. The 1-(4-Aza)8-(6-oxo)oct-(2)en-(1)-oylimidazole binds to penicillin binding proteins, which prevents the formation of an antibiotic inhibitor complex with the enzyme cell wall synthesis that is required for cell wall biosynthesis, inhibiting protein synthesis and cell division. The clavulanic acid moiety in this drug also inhibits beta lactamases produced by bacteria, resulting in increased efficacy against these organisms.
Proprietà chimiche
Richiesta tecnica su: 3D-PDA18634 1-(4-Aza-8-hydroxy-6-oxo)oct-2-en-1-oylimidazole
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