Informazioni sul prodotto
(e)-2-Methyl-3-phenylacrylaldehyde (E2PAA) is a tyrosinase inhibitor that has been shown to inhibit the production of melanin in vitro using human skin cells. E2PAA has been immobilized on magnesium oxide, which prevents it from being washed away by the buffer solution and allows for its use as a reusable catalyst. The uptake of E2PAA was found to be higher when compared to other compounds, such as cis-ddp (1,4-dihydroxynaphthalene), due to its hydrophobic nature. The molecular electrostatic potentials have been calculated for both cis-ddp and E2PAA, which showed that E2PAA has a slightly lower value than cis-ddp. These results indicate that E2PAA is more lipophilic than cis-ddp, which may explain its higher uptake in the skin cells. Structural studies have also
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