Incyclinide
CAS: 15866-90-7
Rif. 3D-QAA86690
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Informazioni sul prodotto
- (4aS,5aR,12aS)-1,4,4a,5,5a,6,11,12a-Octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide
- 2-Naphthacenecarboxamide, 1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-
- 2-Naphthacenecarboxamide, 1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-, (4aS,5aR,12aS)-
- 2-Naphthacenecarboxamide, 1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-, [4aS-(4aα,5aα,12aα)]-
- 4-De(dimethylamino)-6-demethyl-6-deoxytetracycline
- 4-De(dimethylamino)sancycline
- Cmt 3
- Cmt-3,Col-3,Nsc-683551
- Col 3
- Metastat
- Vedi altri sinonimi
- NSC 683551
Incyclinide is a novel, synthetic, cell permeable, small-molecule antibiotic that exhibits high antibacterial efficacy and has been shown to kill cancer cells. This compound has demonstrated inhibitory properties on the activity of matrix metalloproteinases such as MMP-9. Incyclinide also inhibits the production of proinflammatory cytokines such as TNF-α and IL-1β in human monocytes.
The pharmacokinetics of incyclinide have been studied in humans. The drug is rapidly absorbed with a bioavailability of 100% and reaches peak plasma concentrations within 1 hour after administration. It is excreted unchanged in urine, mainly through glomerular filtration, with an elimination half life of 8 hours.
Proprietà chimiche
Richiesta tecnica su: 3D-QAA86690 Incyclinide
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