1-(3-tert-Butylphenyl)methanamine
CAS: 140401-55-4
Rif. 3D-QFA40155
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Informazioni sul prodotto
1-(3-tert-Butylphenyl)methanamine is a potent and selective inhibitor of the enzyme Tryptophan-2,3-dioxygenase (TDO). TDO is an enzyme that catalyzes the conversion of tryptophan to indolepyruvate in the kynurenine pathway. 1-(3-tert-Butylphenyl)methanamine inhibits this conversion, which leads to increased levels of tryptophan in the body. It has been shown to be effective against a range of analytes, including enzymes, with a low nanomolar and nanomolar range. This drug also has an isostere group that allows it to bind at subpockets on the enzyme active site that would not be accessible by other inhibitors.
1-(3-tert-Butylphenyl)methanamine has been shown to inhibit cell proliferation in cell-based assays as well as
Proprietà chimiche
Richiesta tecnica su: 3D-QFA40155 1-(3-tert-Butylphenyl)methanamine
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