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N-Hydroxy-3-[1-(phenylthio)methyl-1H-1,2,3-triazol-4-yl]benzamide
CAS: 1316652-41-1
Rif. 3D-RCC65241
| 1mg | 108,00 € | ||
| 2mg | 173,00 € | ||
| 5mg | 234,00 € | ||
| 10mg | 366,00 € | ||
| 25mg | 717,00 € |
Informazioni sul prodotto
N-Hydroxy-3-[1-(phenylthio)methyl-1H-1,2,3-triazol-4-yl]benzamide (NHTB) is a histone deacetylase inhibitor that binds to the active site of the enzyme and inhibits its activity. It is selective for class I HDACs over class II HDACs. NHTB has been shown to inhibit acetylation of α-tubulin in vitro and in vivo. The compound also inhibits proliferation of T cells from patients with cutaneous T cell lymphoma and promotes apoptosis. NHTB also has antiangiogenic effects by inhibiting proliferation of endothelial cells.
Proprietà chimiche
Richiesta tecnica su: 3D-RCC65241 N-Hydroxy-3-[1-(phenylthio)methyl-1H-1,2,3-triazol-4-yl]benzamide
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