GNE-317
CAS: 1394076-92-6
Rif. 3D-UFC07692
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Informazioni sul prodotto
GNE-317 is a cancer therapeutic that inhibits the activity of CDK4/6 and is currently in phase II clinical trials. GNE-317 has been shown to be effective in inhibiting tumor growth in mice with metastatic melanoma. The mechanism of action of GNE-317 is by binding to CDK4/6 and inhibiting their activity, which prevents phosphorylation of effector proteins such as S6 kinase. This inhibition leads to a decrease in cell proliferation and an increase in apoptosis.
GNE-317 has been shown to inhibit the growth of human breast cancer cells without affecting normal cells. It also inhibits Hdac, a protein involved in cell signaling pathways that can lead to uncontrolled cell growth, which may be due to its ability to inhibit histone deacetylation.
Proprietà chimiche
Richiesta tecnica su: 3D-UFC07692 GNE-317
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