(S)-Sitagliptin
CAS: 823817-55-6
Rif. 3D-YHB81755
| 5mg | Fuori produzione | ||
| 10mg | Fuori produzione | ||
| 25mg | Fuori produzione | ||
| 50mg | Fuori produzione | ||
| 100mg | Fuori produzione | ||
| 250mg | Fuori produzione |
Informazioni sul prodotto
Sitagliptin S-isomer is a potent inhibitor of the dipeptidyl peptidase-4 (DPP-4) enzyme, which is responsible for the degradation of incretin hormones. It is synthesized by liquid chromatography and involves bond formation between acid derivatives and nucleophilic attack. The reaction is catalyzed by a palladium catalyst, and the product is purified using high-performance liquid chromatography. Sitagliptin S-isomer has been shown to be effective in the treatment of metabolic diseases such as type 2 diabetes, by increasing insulin secretion and reducing glucagon levels. The compound undergoes amide bond cleavage by phosphoric acid or copper, which leads to the formation of its active form. This process involves nitrogen atoms acting as a catalytic site for amide bond cleavage.
