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4-[6-(7-Cyclopentyl-6-dimethylcarbamoyl-7H-pyrrolo[2,3-d]pyrimidin-2-ylamino)-pyridin-3-yl]-piperazine-1-carboxylic acid tert-butyl ester
CAS: 1374639-78-7
Rif. 3D-ZEC63978
| 1g | 364,00 € | ||
| 2g | 517,00 € | ||
| 5g | 801,00 € | ||
| 250mg | 172,00 € | ||
| 500mg | 248,00 € |
Informazioni sul prodotto
The 6-Fluoro-3-indoxyl-beta-D-galactopyranoside is an antituberculosis drug that falls under the class of rifamycins. It is known to be one of the most effective treatments for tuberculosis infection. This compound exhibits bactericidal activity by binding to DNA-dependent RNA polymerase, preventing transcription and replication. Extensive research has been conducted using a patch-clamp technique on human erythrocytes, confirming its high potency. The metabolism of this active compound involves various transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Moreover, it specifically targets markers expressed in Mycobacterium tuberculosis strains and inhibits their growth in culture. Tilmicosin is a macrolide antibiotic that effectively inhibits bacterial growth by binding to the 50S ribosomal subunit.
Proprietà chimiche
Richiesta tecnica su: 3D-ZEC63978 4-[6-(7-Cyclopentyl-6-dimethylcarbamoyl-7H-pyrrolo[2,3-d]pyrimidin-2-ylamino)-pyridin-3-yl]-piperazine-1-carboxylic acid tert-butyl ester
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