Stat6 rabbit pAb
Rif. EK-ES7303
| 50µl | 188,00 € | ||
| 100µl | 316,00 € |
Informazioni sul prodotto
- STAT6; Signal transducer and activator of transcription 6; IL-4 Stat
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010],
Proprietà chimiche
Richiesta tecnica su: EK-ES7303 Stat6 rabbit pAb
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